{"id":1539,"date":"2015-03-27T20:23:29","date_gmt":"2015-03-27T11:23:29","guid":{"rendered":"https:\/\/synapse.dept.med.gunma-u.ac.jp\/?post_type=members_2020&p=1539"},"modified":"2020-11-05T18:39:26","modified_gmt":"2020-11-05T09:39:26","slug":"%e7%b4%b0%e4%ba%95%e3%80%80%e5%bb%b6%e6%ad%a6","status":"publish","type":"members_2020","link":"https:\/\/synapse.dept.med.gunma-u.ac.jp\/?members_2020=%e7%b4%b0%e4%ba%95%e3%80%80%e5%bb%b6%e6%ad%a6","title":{"rendered":"\u7d30\u4e95\u3000\u5ef6\u6b66"},"content":{"rendered":"

\u51fa\u8eab\u5730\uff1a \u6803\u6728\u770c\u5b87\u90fd\u5bae\u5e02
\n\u8840\u6db2\u578b\uff1a B\u578b<\/p>\n

\u81ea\u5df1\u7d39\u4ecb<\/h4>\n

\u5b66\u90e8\u751f\u306e\u3053\u308d\u304b\u3089\u3001\u4e00\u8cab\u3057\u3066\u30d1\u30c3\u30c1\u30af\u30e9\u30f3\u30d7\u6cd5\u3092\u7528\u3044\u3066\u3001\u30b7\u30ca\u30d7\u30b9\u4f1d\u9054\u306e\u30e1\u30ab\u30cb\u30ba\u30e0\u306b\u3064\u3044\u3066\u7814\u7a76\u3092\u884c\u3063\u3066\u304d\u307e\u3057\u305f\u3002\u535a\u58eb\u53f7\u53d6\u5f97\u5f8c\u3001\u30c9\u30a4\u30c4\u306eErwin Neher\u5148\u751f\u306e\u7814\u7a76\u5ba4\u306b\u7559\u5b66\u3057\u3001Ca imaging\u3068\u30d1\u30c3\u30c1\u30af\u30e9\u30f3\u30d7\u6cd5\u3092\u7d44\u307f\u5408\u308f\u305b\u3066\u3001\u30b7\u30ca\u30d7\u30b9\u5c0f\u80de\u30b5\u30a4\u30af\u30ea\u30f3\u30b0\u306e\u7814\u7a76\u3092\u884c\u3063\u3066\u304d\u307e\u3057\u305f\u3002\u4eca\u5f8c\u306f\u3001\u30d1\u30c3\u30c1\u30af\u30e9\u30f3\u30d7\u6cd5\u3068\u30a4\u30e1\u30fc\u30b8\u30f3\u30b0\u6280\u8853\u306b\u52a0\u3048\u3066\u3001\u5206\u5b50\u751f\u7269\u5b66\u7684\u624b\u6cd5\u3092\u7d44\u307f\u5408\u308f\u305b\u305f\u65b0\u305f\u306a\u7814\u7a76\u3092\u5c55\u958b\u3057\u3066\u3044\u304d\u305f\u3044\u3068\u601d\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n

\u7814\u7a76\u5ba4\u306b\u3064\u3044\u3066<\/h4>\n

\u96fb\u6c17\u751f\u7406\u5b66\u3068\u5206\u5b50\u751f\u7269\u5b66\u306b\u95a2\u3059\u308b\u5b9f\u9a13\u6a5f\u5668\u304c\u30d0\u30e9\u30f3\u30b9\u3088\u304f\u5145\u5b9f\u3057\u3066\u304a\u308a\u3001\u3055\u3089\u306b\u30a4\u30e1\u30fc\u30b8\u30f3\u30b0\u306e\u5b9f\u9a13\u88c5\u7f6e\u3082\u6574\u3044\u3064\u3064\u3042\u308b\u306e\u3067\u3001\u3068\u3066\u3082\u6075\u307e\u308c\u305f\u5b9f\u9a13\u74b0\u5883\u3060\u3068\u601d\u3044\u307e\u3059\u3002<\/p>\n

\u30d7\u30ed\u30d5\u30a3\u30fc\u30eb<\/h4>\n

2004<\/h5>\n

\u6771\u4eac\u5927\u5b66\u4eba\u6587\u793e\u4f1a\u7cfb\u7814\u7a76\u79d1<\/p>\n

\u5fc3\u7406\u5b66\u5c02\u9580\u5206\u91ce\u3000\u6307\u5c0e\u6559\u5b98\u3000\u7acb\u82b1\u653f\u592b\u6559\u6388<\/p>\n

\u96fb\u6c17\u751f\u7406\u5b66\u306e\u624b\u6cd5\u3092\u7528\u3044\u305f\u7db2\u819c\u5185\u306e\u30b7\u30ca\u30d7\u30b9\u4f1d\u9054\u306e\u7814\u7a76<\/p>\n

\u300c\u521d\u671f\u8996\u899a\u60c5\u5831\u51e6\u7406\u306e\u795e\u7d4c\u6a5f\u69cb\u300d\u535a\u58eb\uff08\u5fc3\u7406\u5b66\uff09\u5b66\u4f4d\u53d6\u5f97<\/p>\n

2004\uff0d2009.03<\/h5>\n

\u30dd\u30b9\u30c9\u30af\u751f\u6d3b\u3000\uff08\u30c9\u30a4\u30c4\u3001\u30b2\u30c3\u30c6\u30a3\u30f3\u30b2\u30f3\uff09<\/p>\n

Department of Membrane Biophysics<\/p>\n

(Prof. Erwin Neher)<\/p>\n

Max Planck Institute for Biophysical Chemistry<\/p>\n

Ratiometric Ca imaging\u3068Ca uncaging\u306e\u624b\u6cd5\u3092\u4f7f\u3063\u3066\u3001<\/p>\n

\u30b7\u30ca\u30d7\u30b9\u4f1d\u9054\u306b\u3064\u3044\u3066\u3001\u30b7\u30ca\u30d7\u30b9\u524d\u7d30\u80de\u5074\u306e\u30e1\u30ab\u30cb\u30ba\u30e0\u3092\u7814\u7a76<\/p>\n

2009.04<\/h5>\n

\u7fa4\u99ac\u5927\u5b66\u5927\u5b66\u9662\u533b\u5b66\u7cfb\u7814\u7a76\u79d1\u3000\u795e\u7d4c\u751f\u7406\u5b66\u5206\u91ce\u3000\u52a9\u6559<\/p>\n

\u7814\u7a76\u696d\u7e3e<\/h4>\n

Disruption of metabotropic glutamate receptor signalling is a major\u3000defect at cerebellar parallel fibre-Purkinje cell synapses in\u3000staggerer mutant mice.
\nMitsumura K, Hosoi N<\/span>, Furuya N, Hirai H.
\nJ Physiol. 2011 Jul 1;589(Pt 13):3191-209. Epub 2011 May 9.<\/p>\n

Calcium dependence of exo- and endocytotic coupling at a glutamatergic synapse.
\nHosoi N<\/span>, Holt M, Sakaba T.
\nNeuron. 2009 Jul 30;63(2):216-29.<\/p>\n

Quantitative analysis of calcium-dependent vesicle recruitment and its\u3000functional role at the calyx of Held synapse.
\nHosoi N<\/span>, Sakaba T, Neher E.
\nJ Neurosci. 2007 Dec 26;27(52):14286-98.<\/p>\n

Group III metabotropic glutamate receptors and exocytosed protons\u3000inhibit L-type calcium currents in cones but not in rods.
\nHosoi N<\/span>, Arai I, Tachibana M.
\nJ Neurosci. 2005 Apr 20;25(16):4062-72.<\/p>\n","protected":false},"featured_media":0,"template":"","class_2020":[48],"class_list":["post-1539","members_2020","type-members_2020","status-publish","hentry","class_2020-teacher"],"acf":[],"_links":{"self":[{"href":"https:\/\/synapse.dept.med.gunma-u.ac.jp\/index.php?rest_route=\/wp\/v2\/members_2020\/1539","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/synapse.dept.med.gunma-u.ac.jp\/index.php?rest_route=\/wp\/v2\/members_2020"}],"about":[{"href":"https:\/\/synapse.dept.med.gunma-u.ac.jp\/index.php?rest_route=\/wp\/v2\/types\/members_2020"}],"wp:attachment":[{"href":"https:\/\/synapse.dept.med.gunma-u.ac.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1539"}],"wp:term":[{"taxonomy":"class_2020","embeddable":true,"href":"https:\/\/synapse.dept.med.gunma-u.ac.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fclass_2020&post=1539"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}