{"id":2909,"date":"2025-07-31T09:47:22","date_gmt":"2025-07-31T00:47:22","guid":{"rendered":"https:\/\/synapse.dept.med.gunma-u.ac.jp\/?p=2909"},"modified":"2025-07-31T11:36:21","modified_gmt":"2025-07-31T02:36:21","slug":"%e3%83%9f%e3%82%af%e3%83%ad%e3%82%b0%e3%83%aa%e3%82%a2%e6%a8%99%e7%9a%84aav%e3%83%99%e3%82%af%e3%82%bf%e3%83%bc%ef%bc%9a%e9%9d%92%e6%9c%a8-%e9%81%bc-%e7%89%b9%e4%bb%bb%e5%8a%a9%e6%95%99%e3%81%ae","status":"publish","type":"post","link":"https:\/\/synapse.dept.med.gunma-u.ac.jp\/?p=2909","title":{"rendered":"\u30df\u30af\u30ed\u30b0\u30ea\u30a2\u6a19\u7684AAV\u30d9\u30af\u30bf\u30fc\uff1a\u9752\u6728 \u907c \u7279\u4efb\u52a9\u6559\u306e\u8ad6\u6587\u304cCell Reports Methods\u306b\u63b2\u8f09\u3055\u308c\u307e\u3057\u305f\u3002"},"content":{"rendered":"<p><a href=\"https:\/\/synapse.dept.med.gunma-u.ac.jp\/wp-content\/uploads\/2025\/07\/Cover_Design_Jul_17_2025_RGB-1.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-2927 alignright\" src=\"https:\/\/synapse.dept.med.gunma-u.ac.jp\/wp-content\/uploads\/2025\/07\/Cover_Design_Jul_17_2025_RGB-1.jpg\" alt=\"\" width=\"232\" height=\"274\" srcset=\"https:\/\/synapse.dept.med.gunma-u.ac.jp\/wp-content\/uploads\/2025\/07\/Cover_Design_Jul_17_2025_RGB-1.jpg 1083w, https:\/\/synapse.dept.med.gunma-u.ac.jp\/wp-content\/uploads\/2025\/07\/Cover_Design_Jul_17_2025_RGB-1-254x300.jpg 254w, https:\/\/synapse.dept.med.gunma-u.ac.jp\/wp-content\/uploads\/2025\/07\/Cover_Design_Jul_17_2025_RGB-1-867x1024.jpg 867w, https:\/\/synapse.dept.med.gunma-u.ac.jp\/wp-content\/uploads\/2025\/07\/Cover_Design_Jul_17_2025_RGB-1-768x907.jpg 768w\" sizes=\"auto, (max-width: 232px) 100vw, 232px\" \/><\/a>\u9752\u6728\u3055\u3093\u304c\u535a\u58eb\u8ab2\u7a0b\u306e3\u5e74\u9593\u3092\u304b\u3051\u3066\u958b\u767a\u3057\u305f\u300c<span style=\"color: #993300;\"><strong>\u30df\u30af\u30ed\u30b0\u30ea\u30a2\u6a19\u7684AAV\u30d9\u30af\u30bf\u30fc<\/strong><\/span>\u300d\u304c<em><strong>Cell Reports Methods<\/strong><\/em>\u306b\u63b2\u8f09\u3055\u308c\u307e\u3057\u305f\u3002\u30c7\u30fc\u30bf\u81ea\u4f53\u306f\u304b\u306a\u308a\u524d\u304b\u3089\u51fa\u3066\u3044\u3066\u3001\u30d3\u30c3\u30b0\u30b8\u30e3\u30fc\u30ca\u30eb\u3092\u76ee\u6307\u3057\u3066\u3044\u305f\u306e\u3067\u3059\u304c\u3001\u5b66\u4f4d\u8ad6\u6587\u3067\u3042\u3063\u305f\u305f\u3081\u30c8\u30e9\u30f3\u30b9\u30d5\u30a1\u30fc\u306e\u6253\u8a3a\u304c\u8907\u6570\u3042\u3063\u305f\u4e2d\u304b\u3089Cell Reports Methods\u3092\u9078\u3093\u3067\u51fa\u7248\u3068\u306a\u308a\u307e\u3057\u305f\u3002<\/p>\n<p>in vivo\u306e\u30df\u30af\u30ed\u30b0\u30ea\u30a2\u3078\u306e\u9078\u629e\u7684\u3001\u304b\u3064\u52b9\u7387\u7684\u306a\u767a\u73fe\u3001\u7279\u306b\u9759\u8108\u5185\u6295\u4e0e\u306b\u3088\u308b\u30df\u30af\u30ed\u30b0\u30ea\u30a2\u3078\u306e\u907a\u4f1d\u5b50\u767a\u73fe\u306f\u4e16\u754c\u7684\u306b\u3082\u307b\u3068\u3093\u3069\u6210\u529f\u3057\u3066\u304a\u3089\u305a\u3001\u753b\u671f\u7684\u306a\u6210\u679c\u3067\u3059\u3002<\/p>\n<h1>AAV vectors for specific and efficient gene expression in microglia<\/h1>\n<p><span role=\"listitem\"><span class=\"dropBlock\"><a href=\"https:\/\/www.cell.com\/cell-reports-methods\/fulltext\/S2667-2375(25)00152-3#\" aria-expanded=\"false\" data-db-target-for=\"axel_author_au1\" aria-controls=\"axel_author_au1\">Ryo\u00a0Aoki<\/a><\/span><sup class=\"xref\"><a role=\"doc-noteref\">1<\/a><\/sup><\/span>\u00a0\u2219\u00a0<span class=\"corresponding-author\" role=\"listitem\"><span class=\"dropBlock\"><a href=\"https:\/\/www.cell.com\/cell-reports-methods\/fulltext\/S2667-2375(25)00152-3#\" aria-expanded=\"false\" data-db-target-for=\"axel_author_au2\" aria-controls=\"axel_author_au2\">Ayumu\u00a0Konno<\/a><\/span><sup class=\"xref\"><a role=\"doc-noteref\">1<\/a>,<a role=\"doc-noteref\">2<\/a><\/sup><\/span>\u00a0\u2219\u00a0<span role=\"listitem\"><span class=\"dropBlock\"><a href=\"https:\/\/www.cell.com\/cell-reports-methods\/fulltext\/S2667-2375(25)00152-3#\" aria-expanded=\"false\" data-db-target-for=\"axel_author_au3\" aria-controls=\"axel_author_au3\">Nobutake\u00a0Hosoi<\/a><\/span><sup class=\"xref\"><a role=\"doc-noteref\">1<\/a><\/sup><\/span>\u00a0\u2219\u00a0<span role=\"listitem\"><span class=\"dropBlock\"><a href=\"https:\/\/www.cell.com\/cell-reports-methods\/fulltext\/S2667-2375(25)00152-3#\" aria-expanded=\"false\" data-db-target-for=\"axel_author_au4\" aria-controls=\"axel_author_au4\">Hayato\u00a0Kawabata<\/a><\/span><sup class=\"xref\"><a role=\"doc-noteref\">1<\/a><\/sup><\/span>\u00a0\u2219\u00a0<span class=\"corresponding-author\" role=\"listitem\"><span class=\"dropBlock\"><a href=\"https:\/\/www.cell.com\/cell-reports-methods\/fulltext\/S2667-2375(25)00152-3#\" aria-expanded=\"false\" data-db-target-for=\"axel_author_au5\" aria-controls=\"axel_author_au5\">Hirokazu\u00a0Hirai<\/a><\/span><sup class=\"xref\"><a role=\"doc-noteref\">1<\/a>,<a role=\"doc-noteref\">2<\/a>,<a role=\"doc-noteref\">3<\/a><\/sup><\/span><\/p>\n<p><a href=\"https:\/\/www.cell.com\/cell-reports-methods\/fulltext\/S2667-2375(25)00152-3#mmc1\" target=\"_blank\" rel=\"noopener\">https:\/\/www.cell.com\/cell-reports-methods\/fulltext\/S2667-2375(25)00152-3#mmc1<\/a><\/p>\n<p><span class=\"meta-panel__left-content\"><span class=\"meta-panel__type\">Article<\/span><\/span><span class=\"meta-panel__middle-content\"><span class=\"meta-panel__volumeIssue\"><a href=\"https:\/\/www.cell.com\/crmeth\/newarticles\">Online now<\/a><\/span><span class=\"meta-panel__number\">101116<\/span><span class=\"meta-panel__onlineDate\">July 30, 2025<\/span><\/span><span class=\"meta-panel__right-content\"><span class=\"meta-panel__access meta-panel__access--open\">Open access<\/span><\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u9752\u6728\u3055\u3093\u304c\u535a\u58eb\u8ab2\u7a0b\u306e3\u5e74\u9593\u3092\u304b\u3051\u3066\u958b\u767a\u3057\u305f\u300c\u30df\u30af\u30ed\u30b0\u30ea\u30a2\u6a19\u7684AAV\u30d9\u30af\u30bf\u30fc\u300d\u304cCell Reports Methods\u306b\u63b2\u8f09\u3055\u308c\u307e\u3057\u305f\u3002\u30c7\u30fc\u30bf\u81ea\u4f53\u306f\u304b\u306a\u308a\u524d\u304b\u3089\u51fa\u3066\u3044\u3066\u3001\u30d3\u30c3\u30b0\u30b8\u30e3\u30fc\u30ca\u30eb\u3092\u76ee\u6307\u3057\u3066\u3044\u305f\u306e\u3067\u3059\u304c\u3001\u5b66\u4f4d\u8ad6\u6587\u3067 [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[22],"tags":[],"class_list":["post-2909","post","type-post","status-publish","format-standard","hentry","category-publications"],"acf":[],"_links":{"self":[{"href":"https:\/\/synapse.dept.med.gunma-u.ac.jp\/index.php?rest_route=\/wp\/v2\/posts\/2909","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/synapse.dept.med.gunma-u.ac.jp\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/synapse.dept.med.gunma-u.ac.jp\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/synapse.dept.med.gunma-u.ac.jp\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/synapse.dept.med.gunma-u.ac.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=2909"}],"version-history":[{"count":7,"href":"https:\/\/synapse.dept.med.gunma-u.ac.jp\/index.php?rest_route=\/wp\/v2\/posts\/2909\/revisions"}],"predecessor-version":[{"id":2928,"href":"https:\/\/synapse.dept.med.gunma-u.ac.jp\/index.php?rest_route=\/wp\/v2\/posts\/2909\/revisions\/2928"}],"wp:attachment":[{"href":"https:\/\/synapse.dept.med.gunma-u.ac.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=2909"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/synapse.dept.med.gunma-u.ac.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=2909"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/synapse.dept.med.gunma-u.ac.jp\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=2909"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}