Fukai Y, Konno A, Hosoi N, Miyakawa K, Kaneko R, Hirai H.
A compact glutamic acid decarboxylase 67 promoter enables inhibitory neuron-targeted AAV gene therapy for treatment-resistant epilepsy
bioRxiv. 2025 Dec 10. doi: https://doi.org/10.64898/2025.12.07.692482

Matsuzaki Y, Konno A, Uchida Y, Terasaki T, Hirai H.
VCAP-102 Achieves Exceptional BBB Penetration in Marmosets After Ten Years of AAV Capsid Evaluation
bioRxiv. 2025 Dec 09. doi: https://doi.org/10.64898/2025.12.06.692617

Knak PG, Vittani M, Lee AB, Nedergaard L, Elleholm NV, Wang X, Bojarowska Z, Martens MC, Konno A, Hirai H, Nedergaard M, Hirase H.
Towards enhancing photostability and adeno-associated viral vector delivery for genetically encoded plasma fluorescent labels
Neurophotonics. 2025 Jun;12(Suppl 2):S22811. doi: 10.1117/1.NPh.12.S2.S22811.

Adachi N, Koganemaru I, Wanying F, Matsushita N, Nakayama T, Seki T, Konno A, Hirai H, Saito N, Ueyama T.
Age-Progressive Synaptic and Axonal Dysregulation Induced by Purkinje Cell-Targeted AAV Expression of SCA14 PKCγ in Mice
J Neurochem. 2025 Nov;169(11):e70305. doi: 10.1111/jnc.70305.

Aoki R, Konno A, Hosoi N, Kawabata H, Hirai H.
AAV vectors for specific and efficient gene expression in microglia
Cell Rep Methods. 2025 Aug 18;5(8):101116. doi: 10.1016/j.crmeth.2025.101116.

Kohno D, Kawabata-Iwakawa R, Ichinose S, Suyama S, Ohashi K, Ariyani W, Sadakata T, Yokota-Hashimoto H, Kobayashi R, Horii T, Susanti VY, Konno A, Tsuneoka H, Yoshikawa C, Matsui S, Harada A, Yada T, Hatada I, Hirai H, Nishiyama M, Sasaki T, Kitamura T.
FTO promotes weight gain via altering Kif1a splicing and axonal vesicle trafficking in AgRP neurons
EMBO J. 2025 Jul 9. doi: 10.1038/s44318-025-00503-3. Online ahead of print.

Vittani M, Herlo R, Wang X, Christensen MDB, Vo CT, Mishima T, Kusk P, Konno A, Hirai H, Tsuboi T, Kitaguchi T, Kjaerby C, Asiminas A, Yokoyama T, Sakamoto M, Nedergaard M, Hirase H.
Cerebral blood flow is modulated by astrocytic cAMP elevation independently of IP3R2-mediated Ca2+ signaling in mice
Proc Natl Acad Sci U S A. 2025 Jul 8;122(27):e2422069122. doi: 10.1073/pnas.2422069122. Epub 2025 Jul 1.

Vittani M, Lee AB, Wang X, Hiraoka Y, Konno A, Knak PG, Kusk P, Nagao M, Asiminas A, Courtin J, Putranto MF, Nasu Y, Tsuno S, Ueda K, Osuga Y, Tsuboi T, Bienvenu T, Terunuma M, Hirai H, Nedergaard M, Tanaka K, Hirase H.
Functional and structural profiling of circulation via genetically encoded modular fluorescent probes
bioRxiv [Preprint]. 2025 Mar 18:2025.03.18.643859. doi: 10.1101/2025.03.18.643859.

Pan M, Liu PW, Ozawa Y, Arima-Yoshida F, Dong G, Sawahata M, Mori D, Nagase M, Fujii H, Ueda S, Yabuuchi Y, Liu X, Narita H, Konno A, Hirai H, Ozaki N, Yamada K, Kidokoro H, Bito H, Mizoguchi H, M Watabe A, Horigane SI, Takemoto-Kimura S.
A hyper-activatable CAMK2A variant associated with intellectual disability causes exaggerated long-term potentiation and learning impairments.
Transl Psychiatry. 2025 Mar 26;15(1):95. doi: 10.1038/s41398-025-03316-4.

Sadakata M, Konno A, Takase A, Kasamatsu T, Iijima T, Hirai H, Sadakata T.
Critical factors for flow cytometry analysis of the brain.
FEBS J. 2025 Jul;292(13):3412-3429. doi: 10.1111/febs.70063. Epub 2025 Mar 14.